Organic phosphoric acids and derivatives
Medchemexpress LLC Sn-Glycerol 3-phosphate | 17989-41-2 | >=98.0% | 172.07 | 1 ML
sn-Glycerol 3-phosphate is a crucial intermediate involved in glycolysis and lipid metabolism. It is produced by the cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) from dihydroxyacetone phosphate (DHAP) and is also a key supplier for lipid metabolism through glyceroneogenesis.
- Important intermediate in glycolysis and lipid metabolism.
- Generated from dihydroxyacetone phosphate (DHAP) by cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH).
- Plays a role in glyceroneogenesis as a supplier for lipid metabolism.
- Stable salt forms, such as sn-Glycerol 3-phosphate lithium, retain similar biological activity.
Strem, An Ascensus Company CAS# 39648-67-4. 1g. (R)-(-)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate, min. 98%. MFCD00010045
CAS# 39648-67-4. 1g. (R)-(-)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate, min. 98%. MFCD00010045. Molecular Weight: 348.30. Molecular Formula: C20H13O4P. Color/form: white pwdr. Strem# 15-0052. http://www.strem.com/catalog/v/15-0052/
Medchemexpress LLC 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine (sodium) | 90693-88-2 | 98.0% | C42H77NNaO10P | 250 MG
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine (sodium) | 90693-88-2 | 98.0% | C42H77NNaO10P | 250 MG
Medchemexpress LLC 1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol) | 24529-88-2 | 99.96% | C39H72O5 | 100 MG
1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol) is a glycerolipid found on the plasma membrane. It is composed of two fatty acid chains linked to a single glycerol molecule via an ester bond. This compound serves as an analog of diacylglycerol (DAG), a second messenger that activates protein kinase C. It has also been utilized as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay and can induce acrosome reaction in human sperm.
- Glycerolipid located on the plasma membrane.
- Analog of the protein kinase C-activating second messenger DAG.
- Used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay.
- Can induce acrosome reaction in human sperm.
- High purity of 99.96%.
- Supplied as a liquid with a density of 0.9218 g/cm³ and a colorless to light yellow appearance.
Medchemexpress LLC LysoPC(16:1(9Z)) | 76790-27-7 | 98.3% | 493.61 | 1 MG
LysoPC(16:1(9Z)) is a type of lysophosphatidylcholine that is used to study spleen deficiency syndrome. It appears as a colorless to light yellow liquid with a purity of 98.3%.
- Used for research purposes only.
- Available in different quantities and concentrations.
- Ships at room temperature within the continental US.
- Storage at -20°C for two years in solution.
Medchemexpress LLC DOPE-NHS | 1010188-79-0 | C50H87N2O13P | 50 MG
DOPE-NHS is a linker used for conjugating peptides to exosomes and other membrane-based nanoparticles, and for drug delivery applications. It has been utilized to conjugate mesenchymal stem cell (MSC)-derived exosomes with rabies viral glycoprotein and exosomes with cardiac homing peptide.
- Can be used for conjugating peptides to exosomes
- Can be used for conjugating peptides to other membrane-based nanoparticles
- Utilized for drug delivery purposes
- Used to conjugate mesenchymal stem cell (MSC)-derived exosomes with rabies viral glycoprotein
- Used to conjugate exosomes with cardiac homing peptide
Medchemexpress LLC DOPE-NHS | 1010188-79-0 | C50H87N2O13P | 5 MG
DOPE-NHS is a linker used for conjugating peptides to exosomes and other membrane-based nanoparticles. It is also suitable for drug delivery applications.
- Allows peptides to be conjugated to exosomes and membrane-based nanoparticles
- Can be used for drug delivery
- Facilitates conjugation of MSC derived exosomes with rabies viral glycoprotein
- Enables conjugation of exosomes with cardiac homing peptide
Medchemexpress LLC (±)-1-Hexadecanoyl-3-chloropropane-dd5-diol | 1189718-15-7 | C19H32D5ClO3 | 1 MG
(±)-1-Hexadecanoyl-3-chloropropane-dd5-diol is a deuterium-labeled compound intended for use as a laboratory chemical and for the manufacture of substances. Stable heavy isotopes have been incorporated into drug molecules as tracers for quantitation during drug development. This product is for research use only and has not been fully validated for medical applications.
- Deuterium-labeled compound
- Suitable for use as laboratory chemical
- Can be used for the manufacture of substances
- For research use only
Medchemexpress LLC 9,11,15-trioxa-6-aza-10-phosphatritriacont-24-enoic acid, 10-hydroxy-5,16-dioxo-13-[(9Z)-1-oxo | 228706-30-7 | ≥98.0% | 858.13 g·mol⁻¹ | C46H84NO11P | 10 MG
DOPE-GA is a phospholipid reagent used in research to prepare liposomes for drug delivery and related applications. It is reported as a key raw material for preparing the liposome ELL-12 and may affect liposome structure, stability, and interactions with cells. Supplied for research use only.
Medchemexpress LLC 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium | 169051-60-9 | 98.0% | 670.87 | 1 MG
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite. It is used in the generation of micelles, liposomes, and artificial membranes. Phosphatidic acids are biologically active lipids that can stimulate a large range of responses in many different cell types. These responses include:
- Platelet aggregation
- Smooth muscle contraction
- In vivo vasoactive effects
- Chemotaxis
- Expression of adhesion molecules
- Increased tight junction permeability of endothelial cells
- Induction of stress fibers
- Modulation of cardiac contractility
Medchemexpress LLC DOPE | 4004-05-1 | 99.96% | 744.03 | 50 MG
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid that combines with cationic phospholipids to improve the transfection efficiency of naked siRNA, and it is also an endogenous metabolite. In studies, DOPE-containing liposomes (LNP) exhibited a knock-down (KD) effect on macrophages and dendritic cells and showed fusogenicity. LNP/siRNA significantly suppressed CD45 protein expression, demonstrating potential as an efficient siRNA delivery system for both murine and human macrophages and dendritic cells.
- Neutral helper lipid for cationic liposomes
- Improves transfection efficiency of naked siRNA
- Exerts knock-down (KD) effect on macrophages and dendritic cells
- Liposomes containing DOPE show fusogenicity
- Potential for efficient siRNA delivery system
- Endogenous metabolite